Good agreement of conventional and gel-based direct agglutination test in immune-mediated haemolytic anaemia
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چکیده
منابع مشابه
Good agreement of conventional and gel-based direct agglutination test in immune-mediated haemolytic anaemia
BACKGROUND The aim of this study was to compare a gel-based test with the traditional direct agglutination test (DAT) for the diagnosis of immune-mediated haemolytic anaemia (IMHA). METHODS Canine (n = 247) and feline (n = 74) blood samples were submitted for DAT testing to two laboratories. A subset of canine samples was categorized as having idiopathic IMHA, secondary IMHA, or no IMHA. RE...
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The immune haemolytic anaemias comprise a set of diseases characterized by shortened red blood cell survival (haemolysis) mediated by the action of antibodies and serum complement. The haemolysis is evidenced by a raised reticulocyte count in the absence of blood loss. Activity of the immune system is diagnosed by the presence of antibody or fragments of complement components (mainly C3 and C4)...
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BACKGROUND Diagnosing canine immune-mediated haemolytic anaemia (IMHA) is often challenging because all currently available tests have their limitations. Dogs with IMHA often have an increased erythrocyte osmotic fragility (OF), a characteristic that is sometimes used in the diagnosis of IMHA. Since the classic osmotic fragility test (COFT) is time-consuming and requires specialized equipment, ...
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ژورنال
عنوان ژورنال: Acta Veterinaria Scandinavica
سال: 2012
ISSN: 1751-0147
DOI: 10.1186/1751-0147-54-10